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Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice

Tryptophan is reportedly the most potent agonist for GPR142. Glucose-stimulated insulin secretion (GSIS) from pancreatic beta cells are enhanced by GPR142-mediated signal. It is not clear, however, if GPR142-mediated signals is solely attributable to GSIS enhancement after tryptophan load in various...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ueda, Yoko, Iwakura, Hiroshi, Bando, Mika, Doi, Asako, Ariyasu, Hiroyuki, Inaba, Hidefumi, Morita, Shuhei, Akamizu, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995358/
https://ncbi.nlm.nih.gov/pubmed/29889885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198762
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