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Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
The endoplasmic reticulum (ER) localized unfolded protein response (UPR) sensors, IRE1α, PERK, and ATF6α, are activated by the accumulation of misfolded proteins in the ER. It is unclear how the endogenous UPR sensors are regulated by both ER stress and the ER luminal chaperone BiP, which is a negat...
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| Publicat a: | Mol Biol Cell |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5994896/ https://ncbi.nlm.nih.gov/pubmed/29851562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-10-0594 |
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