Immunoglobulin G Fragment Crystallizable Glycosylation After Hematopoietic Stem Cell Transplantation Is Dissimilar to Donor Profiles

Immunoglobulin G (IgG) fragment crystallizable (Fc) N-glycosylation has a large influence on the affinity of the antibody for binding to Fcγ-receptors (FcγRs) and C1q protein, thereby influencing immune effector functions. IgG Fc glycosylation is known to be partly regulated by genetics and partly b...

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Publicado en:Front Immunol
Autores principales: de Haan, Noortje, van Tol, Maarten J. D., Driessen, Gertjan J., Wuhrer, Manfred, Lankester, Arjan C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994695/
https://ncbi.nlm.nih.gov/pubmed/29915589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01238
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