Early Striatal Amyloid Deposition Distinguishes Down Syndrome and Autosomal Dominant AD from Late Onset Amyloid Deposition

OBJECTIVE: To evaluate Aβ deposition patterns in different groups of cerebral β-amyloidosis: 1) non-demented with amyloid precursor protein (APP) overproduction [Down syndrome (DS)]; 2) non-demented with abnormal processing of APP [autosomal dominant Alzheimer disease (preADAD)]; presumed alteration...

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Publicado en:Alzheimers Dement
Main Authors: Cohen, Ann D., McDade, Eric, Christian, Brad, Price, Julie, Mathis, Chester, Klunk, William, Handen, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994364/
https://ncbi.nlm.nih.gov/pubmed/29477284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.01.002
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