Peptidoglycan Suppresses Phagocytic Activities and Apoptosis of Macrophages in Colonic Mucosa Tissues of Crohn’s Disease Patients and In Vitro

BACKGROUND: Rac1 signaling plays a crucial role in controlling macrophage functions in CD. Peptidoglycan triggers several intracellular signaling pathways, including activation of Rac1, to regulate the function of macrophage. Suppressed Rac1 signaling in non-inflamed colonic mucosa of Crohn’s diseas...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Jing, Yang, Ran, Ying, Zhao, Jing, Zhou, Zhe, Zhang, Jun, Qian, Yiqi, Yin, Zhiqi, Zhang, Mingfang, Lv, Zongshun, Zhou, Lu, Wang, Bangmao
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Lab/In Vitro Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994142/
https://ncbi.nlm.nih.gov/pubmed/29787559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910266
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