A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II

Mucopolysaccharidosis II (MPS II) is an X-linked recessive lysosomal storage disease caused by mutations in the iduronate-2-sulfatase (IDS) gene. Since IDS catalyzes the degradation of glycosaminoglycans (GAGs), deficiency in this enzyme leads to accumulation of GAGs in most cells in all tissues and...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Ther
Autores principales: Sonoda, Hiroyuki, Morimoto, Hideto, Yoden, Eiji, Koshimura, Yuri, Kinoshita, Masafumi, Golovina, Galina, Takagi, Haruna, Yamamoto, Ryuji, Minami, Kohtaro, Mizoguchi, Akira, Tachibana, Katsuhiko, Hirato, Tohru, Takahashi, Kenichi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993955/
https://ncbi.nlm.nih.gov/pubmed/29606503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.02.032
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares