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Quantitative theory of deep brain stimulation of the subthalamic nucleus for the suppression of pathological rhythms in Parkinson’s disease

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is modeled to explore the mechanisms of this effective, but poorly understood, treatment for motor symptoms of drug-refractory Parkinson’s disease and dystonia. First, a neural field model of the corticothalamic-basal ganglia (CTBG) syste...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Müller, Eli J., Robinson, Peter A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993558/
https://ncbi.nlm.nih.gov/pubmed/29813060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006217
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