Increase in PD-L1 expression after pre-operative radiotherapy for soft tissue sarcoma

Soft tissue sarcomas (STS) have minimal expression of PD-L1, a biomarker for PD-1 therapy efficacy. Radiotherapy (RT) has been shown to increase PD-L1 expression pre-clinically. We examined the expression of PD-L1, pre- and post-RT, in 46 Stage II-III STS patients treated with pre-operative RT (50–5...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Patel, Kirtesh R., Martinez, Anthony, Stahl, John M., Logan, Suzanna J., Perricone, Adam J., Ferris, Matthew J., Buchwald, Zachary S., Chowdhary, Mudit, Delman, Keith A., Monson, David K., Oskouei, Shervin V., Reimer, Nicholas B., Cardona, Kenneth, Edgar, Mark A., Godette, Karen D.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993497/
https://ncbi.nlm.nih.gov/pubmed/29900051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1442168
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