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RNA mis-splicing in disease

The human transcriptome is composed of a vast RNA population that undergoes further diversification by splicing. Detecting specific splice sites in this large sequence pool is the responsibility of the major and minor spliceosomes in collaboration with numerous splicing factors. This complexity make...

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Bibliografiske detaljer
Udgivet i:Nat Rev Genet
Main Authors: Scotti, Marina M., Swanson, Maurice S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993438/
https://ncbi.nlm.nih.gov/pubmed/26593421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2015.3
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