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Evaluating the Analgesic Effect of the GLS Inhibitor 6-Diazo-5-Oxo-L-Norleucine in Vivo

Glutamate is an excitatory neurotransmitter, produced by its synthetic enzyme, glutaminase (GLS), and packaged by vesicular transporters (VGluT2) into synaptic vesicles. Primary sensory peripheral nerve and spinal synaptic terminals release glutamate during nociceptive (pain) signaling. In post-inci...

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Detalhes bibliográficos
Publicado no:Pharm Pharmacol Int J
Main Authors: Crosby, Heith A, Miller, Kenneth E
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993434/
https://ncbi.nlm.nih.gov/pubmed/29888760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15406/ppij.2015.03.00055
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