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Continuous DNA replication is required for late gene transcription and maintenance of replication compartments in gammaherpesviruses

Late gene transcription in herpesviruses is dependent on viral DNA replication in cis but the mechanistic basis for this linkage remains unknown. DNA replication results in demethylated DNA, topological changes, removal of proteins and recruitment of proteins to promoters. One or more of these effec...

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Vydáno v:PLoS Pathog
Hlavní autoři: Li, Dajiang, Fu, Wenmin, Swaminathan, Sankar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993329/
https://ncbi.nlm.nih.gov/pubmed/29813138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007070
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