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Continuous DNA replication is required for late gene transcription and maintenance of replication compartments in gammaherpesviruses

Late gene transcription in herpesviruses is dependent on viral DNA replication in cis but the mechanistic basis for this linkage remains unknown. DNA replication results in demethylated DNA, topological changes, removal of proteins and recruitment of proteins to promoters. One or more of these effec...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Li, Dajiang, Fu, Wenmin, Swaminathan, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993329/
https://ncbi.nlm.nih.gov/pubmed/29813138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007070
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