Effects of smoking and body mass index on the exposure of fentanyl in patients with cancer

The transdermal fentanyl patch is widely used to treat cancer-related pain despite its wide inter- and intrapatient variability in pharmacokinetics. The aim of this study was to investigate whether smoking and body size (i.e. body mass index) influence fentanyl exposure in patients with cancer. Thes...

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Vydáno v:PLoS One
Hlavní autoři: Kuip, Evelien J. M., Oldenmenger, Wendy H., Thijs—Visser, Martine F., de Bruijn, Peter, Oosten, Astrid W., Oomen—de Hoop, Esther, Koolen, Stijn L. W., Van der Rijt, Carin C. D., Mathijssen, Ron H. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993275/
https://ncbi.nlm.nih.gov/pubmed/29883454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198289
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