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Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches

Sequencing of Streptomyces genomes has revealed they harbor a high number of biosynthesis gene cluster (BGC), which uncovered their enormous potentiality to encode specialized metabolites. However, these metabolites are not usually produced under standard laboratory conditions. In this manuscript we...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Becerril, Adriana, Álvarez, Susana, Braña, Alfredo F., Rico, Sergio, Díaz, Margarita, Santamaría, Ramón I., Salas, José A., Méndez, Carmen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993118/
https://ncbi.nlm.nih.gov/pubmed/29795673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198145
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