Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches

Sequencing of Streptomyces genomes has revealed they harbor a high number of biosynthesis gene cluster (BGC), which uncovered their enormous potentiality to encode specialized metabolites. However, these metabolites are not usually produced under standard laboratory conditions. In this manuscript we...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Becerril, Adriana, Álvarez, Susana, Braña, Alfredo F., Rico, Sergio, Díaz, Margarita, Santamaría, Ramón I., Salas, José A., Méndez, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993118/
https://ncbi.nlm.nih.gov/pubmed/29795673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198145
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