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A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles

Recent large-scale genome-wide association studies have identified tens of genetic loci robustly associated with Body Mass Index (BMI). Gene expression profiles were also found to be associated with BMI. However, accurate prediction of obesity risk utilizing genetic data remains challenging. In a co...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Joseph, Paule V., Wang, Yupeng, Fourie, Nicolaas H., Henderson, Wendy A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993110/
https://ncbi.nlm.nih.gov/pubmed/29795655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197843
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