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A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles

Recent large-scale genome-wide association studies have identified tens of genetic loci robustly associated with Body Mass Index (BMI). Gene expression profiles were also found to be associated with BMI. However, accurate prediction of obesity risk utilizing genetic data remains challenging. In a co...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Joseph, Paule V., Wang, Yupeng, Fourie, Nicolaas H., Henderson, Wendy A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993110/
https://ncbi.nlm.nih.gov/pubmed/29795655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197843
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