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Loss of heparan sulfate in the niche leads to tumor-like germ cell growth in the Drosophila testis

The stem cell niche normally prevents aberrant stem cell behaviors that lead to cancer formation. Recent studies suggest that some cancers are derived from endogenous populations of adult stem cells that have somehow escaped from normal control by the niche. However, the molecular mechanisms by whic...

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Bibliografische gegevens
Gepubliceerd in:Glycobiology
Hoofdauteurs: Levings, Daniel C, Nakato, Hiroshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993100/
https://ncbi.nlm.nih.gov/pubmed/29069438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx090
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