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Loss of heparan sulfate in the niche leads to tumor-like germ cell growth in the Drosophila testis

The stem cell niche normally prevents aberrant stem cell behaviors that lead to cancer formation. Recent studies suggest that some cancers are derived from endogenous populations of adult stem cells that have somehow escaped from normal control by the niche. However, the molecular mechanisms by whic...

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Detalles Bibliográficos
Publicado en:Glycobiology
Autores principales: Levings, Daniel C, Nakato, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993100/
https://ncbi.nlm.nih.gov/pubmed/29069438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx090
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