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Loss of heparan sulfate in the niche leads to tumor-like germ cell growth in the Drosophila testis

The stem cell niche normally prevents aberrant stem cell behaviors that lead to cancer formation. Recent studies suggest that some cancers are derived from endogenous populations of adult stem cells that have somehow escaped from normal control by the niche. However, the molecular mechanisms by whic...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Levings, Daniel C, Nakato, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993100/
https://ncbi.nlm.nih.gov/pubmed/29069438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx090
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