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Rapid Syntheses of Heteroaryl-substituted Imidazo[1,5-a]indole and Pyrrolo[1,2-c]imidazole via Aerobic C2–H Functionalizations
Here we report an aerobic Pd(0) catalyzed C2–H functionalization of indoles and pyrroles with tethered N-methoxylamide as directing group. A Pd(0)-initiated mechanism overcomes the directing or poisoning effect from a wide range of heterocycles including pyridine, pyrimidine, and thiazole. The imida...
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| Vydáno v: | Org Lett |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993056/ https://ncbi.nlm.nih.gov/pubmed/29256621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03596 |
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