ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells

Cardiac development requires coordinated biphasic regulation of the WNT/β-catenin signaling pathway. By intersecting gene expression and loss-of-function siRNA screens we identified Alpha Protein Kinase 2 (ALPK2) as a candidate negative regulator of WNT/β-catenin signaling in cardiogenesis. In diffe...

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Udgivet i:iScience
Main Authors: Hofsteen, Peter, Robitaille, Aaron Mark, Strash, Nicholas, Palpant, Nathan, Moon, Randall T., Pabon, Lil, Murry, Charles E.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993047/
https://ncbi.nlm.nih.gov/pubmed/29888752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.03.010
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