Shift in VEGFA isoform balance towards more angiogenic variants is associated with tumor stage and differentiation of human hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common and aggressive type of malignant liver tumor. HCC progression depends significantly on its vascularization and formation of new blood vessels. Vascular endothelial growth factor A (VEGFA) is a crucial regulator of tumor vascularization an...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Chesnokov, Mikhail S., Khesina, Polina A., Shavochkina, Darya A., Kustova, Inna F., Dyakov, Leonid M., Morozova, Olga V., Mugue, Nikolai S., Kudashkin, Nikolay E., Moroz, Ekaterina A., Patyutko, Yuri I., Lazarevich, Natalia L.
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993022/
https://ncbi.nlm.nih.gov/pubmed/29888133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4915
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