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Pharmacokinetic-based prediction of real-life dosing of extended half-life clotting factor concentrates on hemophilia

The improvement of clotting factor concentrates (CFCs) has undergone an impressive boost during the last six years. Since 2010, several new recombinant factor (rF)VIII/IX concentrates entered phase I/II/III clinical trials. The improvements are related to the culture of human embryonic kidney (HEK)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ther Adv Hematol
Prif Awduron: Morfini, Massimo, Gherardini, Stefano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992810/
https://ncbi.nlm.nih.gov/pubmed/29899890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620718774258
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