Hamartoma-like lesions in the mouse retina: an animal model of Pten hamartoma tumour syndrome

PTEN hamartoma tumour syndrome (PHTS) is a heterogeneous group of rare, autosomal dominant disorders associated with PTEN germline mutations. PHTS patients routinely develop hamartomas, which are benign tissue overgrowths comprised of disorganized ‘normal’ cells. Efforts to generate PHTS animal mode...

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Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Tachibana, Nobuhiko, Touahri, Yacine, Dixit, Rajiv, David, Luke Ajay, Adnani, Lata, Cantrup, Robert, Aavani, Tooka, Wong, Rachel O., Logan, Cairine, Kurek, Kyle C., Schuurmans, Carol
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992614/
https://ncbi.nlm.nih.gov/pubmed/29716894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031005
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