Hamartoma-like lesions in the mouse retina: an animal model of Pten hamartoma tumour syndrome

PTEN hamartoma tumour syndrome (PHTS) is a heterogeneous group of rare, autosomal dominant disorders associated with PTEN germline mutations. PHTS patients routinely develop hamartomas, which are benign tissue overgrowths comprised of disorganized ‘normal’ cells. Efforts to generate PHTS animal mode...

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Bibliografski detalji
Izdano u:Dis Model Mech
Glavni autori: Tachibana, Nobuhiko, Touahri, Yacine, Dixit, Rajiv, David, Luke Ajay, Adnani, Lata, Cantrup, Robert, Aavani, Tooka, Wong, Rachel O., Logan, Cairine, Kurek, Kyle C., Schuurmans, Carol
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992614/
https://ncbi.nlm.nih.gov/pubmed/29716894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031005
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