Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1

Steinert disease, or myotonic dystrophy type 1 (DM1), is a multisystemic disorder caused by toxic noncoding CUG repeat transcripts, leading to altered levels of two RNA binding factors, MBNL1 and CELF1. The contribution of CELF1 to DM1 phenotypes is controversial. Here, we show that the Drosophila C...

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Bibliografische gegevens
Gepubliceerd in:Dis Model Mech
Hoofdauteurs: Picchio, Lucie, Legagneux, Vincent, Deschamps, Stephane, Renaud, Yoan, Chauveau, Sabine, Paillard, Luc, Jagla, Krzysztof
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992612/
https://ncbi.nlm.nih.gov/pubmed/29716962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031849
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