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Ldb1- and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in the retina

Precise control of the relative ratio of retinal neurons and glia generated during development is essential for visual function. We show that Lhx2, which encodes a LIM-homeodomain transcription factor essential for specification and differentiation of retinal Müller glia, also plays a crucial role i...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: de Melo, Jimmy, Clark, Brian S., Venkataraman, Anand, Shiau, Fion, Zibetti, Cristina, Blackshaw, Seth
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992592/
https://ncbi.nlm.nih.gov/pubmed/29650591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.159970
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