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Adenylyl cyclase A mRNA localized at the back of cells is actively translated in live chemotaxing Dictyostelium

Dictyostelium discoideum cells transport adenylyl cyclase A (ACA)-containing vesicles to the back of polarized cells to relay exogenous cAMP signals during chemotaxis. Fluorescence in situ hybridization (FISH) experiments showed that ACA mRNA is also asymmetrically distributed at the back of polariz...

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Udgivet i:J Cell Sci
Main Authors: Wang, Weiye, Chen, Song, Das, Satarupa, Losert, Wolfgang, Parent, Carole A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992586/
https://ncbi.nlm.nih.gov/pubmed/29618632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.216176
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