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Long-term toxicity, pharmacokinetics and immune effects of a recombinant adenovirus vaccine expressing human papillomavirus 16 E6 and E7 proteins (HPV16 E6E7-Ad5 Vac) in primates
Objective: This study aimed to: evaluate long-term toxicity and pharmacokinetic parameters; to identify the target organ of toxicity of a recombinant adenovirus vaccine expressing human papillomavirus 16 E6 and E7 proteins (HPV16 E6E7-Ad5 Vac) in primates; and to determine the specific immune respon...
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Published in: | Am J Transl Res |
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Main Authors: | , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
e-Century Publishing Corporation
2018
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5992553/ https://ncbi.nlm.nih.gov/pubmed/29887967 |
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