Long-term toxicity, pharmacokinetics and immune effects of a recombinant adenovirus vaccine expressing human papillomavirus 16 E6 and E7 proteins (HPV16 E6E7-Ad5 Vac) in primates

Objective: This study aimed to: evaluate long-term toxicity and pharmacokinetic parameters; to identify the target organ of toxicity of a recombinant adenovirus vaccine expressing human papillomavirus 16 E6 and E7 proteins (HPV16 E6E7-Ad5 Vac) in primates; and to determine the specific immune respon...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Transl Res
Prif Awduron: Wu, Jie, Chen, Gang, Zhuang, Fang-Cheng, Gao, Meng, Wu, Chuan-Dong, He, Zhan-Long, Jiang, Yun-Shui, Li, Jian-Bo, Bao, Jia-Yuan, Mao, Zi-An
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992553/
https://ncbi.nlm.nih.gov/pubmed/29887967
Tagiau: Ychwanegu Tag
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