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Quercetin attenuates myocardial ischemia-reperfusion injury via downregulation of the HMGB1-TLR4-NF-κB signaling pathway

The goal of this study was to assess the ability of quercetin (Qu) to protect against myocardial ischemia-reperfusion injury. Cardiac injury was assessed in the context of global ischemia of isolated hearts, coronary artery ligated rats, and H9C2 cells. Qu was shown to significantly inhibit inflamma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Dong, Li-Ya, Chen, Feng, Xu, Min, Yao, Li-Ping, Zhang, Yun-Jiao, Zhuang, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992549/
https://ncbi.nlm.nih.gov/pubmed/29887944
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