Quercetin attenuates myocardial ischemia-reperfusion injury via downregulation of the HMGB1-TLR4-NF-κB signaling pathway

The goal of this study was to assess the ability of quercetin (Qu) to protect against myocardial ischemia-reperfusion injury. Cardiac injury was assessed in the context of global ischemia of isolated hearts, coronary artery ligated rats, and H9C2 cells. Qu was shown to significantly inhibit inflamma...

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Veröffentlicht in:Am J Transl Res
Hauptverfasser: Dong, Li-Ya, Chen, Feng, Xu, Min, Yao, Li-Ping, Zhang, Yun-Jiao, Zhuang, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992549/
https://ncbi.nlm.nih.gov/pubmed/29887944
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