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Tolerance to paternal genotoxic damage promotes survival during embryo development in zebrafish (Danio rerio)

Spermatozoa carry DNA damage that must be repaired by the oocyte machinery upon fertilization. Different strategies could be adopted by different vertebrates to face the paternal genotoxic damage. Mammals have strong sperm selection mechanisms and activate a zygotic DNA damage response (DDR) (includ...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Fernández-Díez, Cristina, González-Rojo, Silvia, Lombó, Marta, Herráez, M. Paz
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992526/
https://ncbi.nlm.nih.gov/pubmed/29712649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.030130
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