Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis

Cryptotanshinone (CTS) has emerged as an anti-inflammatory agent in osteoarthritis (OA). However, the molecular mechanism underlying its potent therapeutic effect on OA remains largely unknown. MicroRNAs (miRNAs) act as crucial regulators in maintaining cartilage homeostasis. To investigate whether...

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Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Ji, Quanbo, Qi, Dengbin, Xu, Xiaojie, Xu, Yameng, Goodman, Stuart B., Kang, Lei, Song, Qi, Fan, Zhongyi, Maloney, William J., Wang, Yan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992348/
https://ncbi.nlm.nih.gov/pubmed/29858052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.02.001
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