Adaptation of Pseudomonas aeruginosa to Phage PaP1 Predation via O-Antigen Polymerase Mutation

Adaptation of bacteria to phage predation poses a major obstacle for phage therapy. Bacteria adopt multiple mechanisms, such as inhibition of phage adsorption and CRISPR/Cas systems, to resist phage infection. Here, a phage-resistant mutant of Pseudomonas aeruginosa strain PA1 under the infection of...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Li, Gang, Shen, Mengyu, Yang, Yuhui, Le, Shuai, Li, Ming, Wang, Jing, Zhao, Yan, Tan, Yinling, Hu, Fuquan, Lu, Shuguang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992289/
https://ncbi.nlm.nih.gov/pubmed/29910791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01170
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