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Complex Phenotype of Dyskeratosis Congenita and Mood Dysregulation with Novel Homozygous RTEL1 and TPH1 Variants

Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome caused by germline mutations in telomere biology genes. Patients have extremely short telomeres for their age and a complex phenotype including oral leukoplakia, abnormal skin pigmentation and dysplastic nails in addition to bo...

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Bibliografske podrobnosti
izdano v:Am J Med Genet A
Main Authors: Ungar, Rachel A., Giri, Neelam, Pao, Maryland, Khincha, Payal P., Zhou, Weiyin, Alter, Blanche P., Savage, Sharon A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992073/
https://ncbi.nlm.nih.gov/pubmed/29696773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.38706
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