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A diazido mannose analog as a chemoenzymatic synthon for synthesizing di-N-acetyllegionaminic acid-containing glycosides

A novel strategy is developed to expand the scope of chemoenzymatic synthetic products by designing a chemoenzymatic synthon. The synthon is enzymatically converted to carbohydrate analogs which are readily derivatized chemically to produce desired targets. The strategy is demonstrated for synthesiz...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Santra, Abhishek, Xiao, An, Yu, Hai, Li, Wanqing, Li, Yanhong, Ngo, Linh, McArthur, John B., Chen, Xi
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991975/
https://ncbi.nlm.nih.gov/pubmed/29349857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201712022
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