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An Opportunistic Infection Associated With Ruxolitinib, a Novel Janus Kinase 1,2 Inhibitor

We report a case of Cryptococcus neoformans pneumonia in a patient taking ruxolitinib, a janus kinase 1,2 inhibitor approved for the treatment of myelofibrosis. We hypothesize that ruxolitinib contributed to this infection through its effects on cell-mediated immunity. Clinicians should be aware of...

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Библиографические подробности
Опубликовано в: :Chest
Главные авторы: Wysham, Nicholas G., Sullivan, Donald R., Allada, Gopal
Формат: Artigo
Язык:Inglês
Опубликовано: American College of Chest Physicians 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991580/
https://ncbi.nlm.nih.gov/pubmed/23648912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.12-1604
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