Early-life adversity facilitates acquisition of cocaine self-administration and induces persistent anhedonia

Early-life adversity increases the risk for emotional disorders such as depression and schizophrenia. Anhedonia, thought to be a core feature of these disorders, is provoked by our naturalistic rodent model of childhood adversity (i.e., rearing pups for one week in cages with limited bedding and nes...

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Publicado en:Neurobiol Stress
Main Authors: Bolton, Jessica L., Ruiz, Christina M., Rismanchi, Neggy, Sanchez, Gissell A., Castillo, Erik, Huang, Jeff, Cross, Christopher, Baram, Tallie Z., Mahler, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Original Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991313/
https://ncbi.nlm.nih.gov/pubmed/29888304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2018.01.002
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