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Development of a Rapid and Precise Reversed-phase High-performance Liquid Chromatography Method for Analysis of Docetaxel in Rat Plasma: Application in Single-dose Pharmacokinetic Studies of Folate-targeted Micelles Containing Docetaxel

BACKGROUND: A simple and sensitive reversed-phase high-performance liquid chromatography (HPLC) method based on liquid-liquid extraction was established and validated for determination of docetaxel (DTX) in plasma of rat. MATERIALS AND METHODS: Samples were spiked with paclitaxel as the internal sta...

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Detalhes bibliográficos
Publicado no:Adv Biomed Res
Main Authors: Taymouri, Somayeh, Varshosaz, Jaleh, Javanmard, Shaghayegh Haghjooy, Hassanzadeh, Farshid
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991273/
https://ncbi.nlm.nih.gov/pubmed/29930916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/abr.abr_251_16
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