Region-Specific Regulation of Presynaptic Dopamine Homeostasis by D(2) Autoreceptors Shapes the In Vivo Impact of the Neuropsychiatric Disease-Associated DAT Variant Val559

Disruptions of dopamine (DA) signaling contribute to a broad spectrum of neuropsychiatric disorders, including attention-deficit hyperactivity disorder (ADHD), addiction, bipolar disorder, and schizophrenia. Despite evidence that risk for these disorders derives from heritable variation in DA-linked...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gowrishankar, Raajaram, Gresch, Paul J., Davis, Gwynne L., Katamish, Rania M., Riele, Justin R., Stewart, Adele M., Vaughan, Roxanne A., Hahn, Maureen K., Blakely, Randy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990980/
https://ncbi.nlm.nih.gov/pubmed/29739866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0055-18.2018
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