Neuroprotection Targeting Protein Misfolding on Chronic Cerebral Hypoperfusion in the Context of Metabolic Syndrome

Metabolic syndrome (MetS) is a cluster of risk factors that lead to microvascular dysfunction and chronic cerebral hypoperfusion (CCH). Long-standing reduction in oxygen and energy supply leads to brain hypoxia and protein misfolding, thereby linking CCH to Alzheimer's disease. Protein misfoldi...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Herrera, María I., Udovin, Lucas D., Toro-Urrego, Nicolás, Kusnier, Carlos F., Luaces, Juan P., Otero-Losada, Matilde, Capani, Francisco
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990610/
https://ncbi.nlm.nih.gov/pubmed/29904335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00339
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