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Accurate detection of complex structural variations using single molecule sequencing

Structural variations (SVs) are the largest source of genetic variation, but remain poorly understood because of limited genomics technology. Single molecule long-read sequencing from Pacific Biosciences and Oxford Nanopore has the potential to dramatically advance the field, although their high err...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Sedlazeck, Fritz J., Rescheneder, Philipp, Smolka, Moritz, Fang, Han, Nattestad, Maria, von Haeseler, Arndt, Schatz, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990442/
https://ncbi.nlm.nih.gov/pubmed/29713083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0001-7
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