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Microfluidic System for Detection of Viral RNA in Blood Using a Barcode Fluorescence Reporter and a Photocleavable Capture Probe

A microfluidic sample preparation multiplexer (SPM) and assay procedure is developed to improve amplification-free detection of Ebola virus RNA from blood. While a previous prototype successfully detected viral RNA following off-chip RNA extraction from infected cells, the new device and protocol ca...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Du, Ke, Park, Myeongkee, Griffiths, Anthony, Carrion, Ricardo, Patterson, Jean, Schmidt, Holger, Mathies, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990416/
https://ncbi.nlm.nih.gov/pubmed/29073356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b03527
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