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Pigment epithelium‐derived factor/vascular endothelial growth factor ratio plays a crucial role in the spontaneous regression of infant hemangioma and in the therapeutic effect of propranolol

Infantile hemangioma (IH) is a benign tumor that is formed by aberrant angiogenesis and that undergoes spontaneous regression over time. Propranolol, the first‐line therapy for IH, inhibits angiogenesis by downregulating activation of the vascular endothelial growth factor (VEGF) pathway, which is h...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Zhu, Liuqing, Xie, Jinye, Liu, Zhenyin, Huang, Zhijian, Huang, Mao, Yin, Haofan, Qi, Weiwei, Yang, Zhonghan, Zhou, Ti, Gao, Guoquan, Zhang, Jing, Yang, Xia
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989849/
https://ncbi.nlm.nih.gov/pubmed/29664206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13611
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