Pigment epithelium‐derived factor/vascular endothelial growth factor ratio plays a crucial role in the spontaneous regression of infant hemangioma and in the therapeutic effect of propranolol

Infantile hemangioma (IH) is a benign tumor that is formed by aberrant angiogenesis and that undergoes spontaneous regression over time. Propranolol, the first‐line therapy for IH, inhibits angiogenesis by downregulating activation of the vascular endothelial growth factor (VEGF) pathway, which is h...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Zhu, Liuqing, Xie, Jinye, Liu, Zhenyin, Huang, Zhijian, Huang, Mao, Yin, Haofan, Qi, Weiwei, Yang, Zhonghan, Zhou, Ti, Gao, Guoquan, Zhang, Jing, Yang, Xia
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989849/
https://ncbi.nlm.nih.gov/pubmed/29664206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13611
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