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Noise in the Vertebrate Segmentation Clock Is Boosted by Time Delays but Tamed by Notch Signaling

Taming cell-to-cell variability in gene expression is critical for precise pattern formation during embryonic development. To investigate the source and buffering mechanism of expression variability, we studied a biological clock, the vertebrate segmentation clock, controlling the precise spatiotemp...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Keskin, Sevdenur, Devakanmalai, Gnanapackiam S., Kwon, Soo Bin, Vu, Ha T., Hong, Qiyuan, Lee, Yin Yeng, Soltani, Mohammad, Singh, Abhyudai, Ay, Ahmet, Özbudak, Ertuğrul M.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989725/
https://ncbi.nlm.nih.gov/pubmed/29768214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.069
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