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Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch-and Hedgehog-Dependent Tumor-Initiating Cells
Acquired resistance to Docetaxel precedes fatality in hormone-refractory prostate cancer (HRPC). However, strategies that target Docetaxel resistant cells remain elusive. Using in vitro and in vivo models, we identified a subpopulation of cells that survive Docetaxel exposure. This subpopulation lac...
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Publicado no: | Cancer Cell |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5989708/ https://ncbi.nlm.nih.gov/pubmed/22975379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.07.016 |
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