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Cobalt-catalysed alkene hydrogenation: a metallacycle can explain the hydroxyl activating effect and the diastereoselectivity

Bis(phosphine)cobalt dialkyl complexes have been reported to be highly active in the hydrogenation of tri-substituted alkenes bearing hydroxyl substituents. Alkene substrates containing ether, ester, or ketone substituents show minimal reactivity, indicating an activating effect of the hydroxyl grou...

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Pubblicato in:Chem Sci
Autori principali: Morello, Glenn R., Zhong, Hongyu, Chirik, Paul J., Hopmann, Kathrin H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989653/
https://ncbi.nlm.nih.gov/pubmed/29938025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01315b
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