Intravascular Ketamine Increases Theta-Burst but Not High Frequency Tetanus Induced LTP at CA3-CA1 Synapses Within Three Hours and Devoid of an Increase in Spine Density

In the past 20 years, ketamine has become a promising treatment for Major Depressive Disorder (MDD) due to its rapid and sustain antidepressant effects in patients. A single ketamine treatment causes improvement in depressive symptoms within hours and can last weeks, long after it is eliminated. Pre...

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Detalles Bibliográficos
Publicado en:Front Synaptic Neurosci
Autores principales: Widman, Allie J., Stewart, Amy E., Erb, Elise M., Gardner, Elizabeth, McMahon, Lori L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989646/
https://ncbi.nlm.nih.gov/pubmed/29899695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2018.00008
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