Beta-defensin derived cationic antimicrobial peptides with potent killing activity against gram negative and gram positive bacteria

BACKGROUND: Avian β-defensins (AvBD) are cationic antimicrobial peptides (CAMP) with broad-spectrum antimicrobial activity, chemotactic property, and low host cytotoxicity. However, their bactericidal activity is greatly compromised under physiological salt concentrations which limits the use of the...

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Bibliografiske detaljer
Udgivet i:BMC Microbiol
Main Authors: Yang, Ming, Zhang, Chunye, Zhang, Michael Z., Zhang, Shuping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989455/
https://ncbi.nlm.nih.gov/pubmed/29871599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-018-1190-z
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