Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection

Zika virus (ZIKV) has recently caused explosive outbreaks in Pacific islands, South- and Central America. Like with other flaviviruses, protective immunity is strongly dependent on potently neutralizing antibodies (Abs) directed against the viral envelope protein E. Such Ab formation is promoted by...

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Publicado en:Front Immunol
Autores principales: Koblischke, Maximilian, Stiasny, Karin, Aberle, Stephan W., Malafa, Stefan, Tsouchnikas, Georgios, Schwaiger, Julia, Kundi, Michael, Heinz, Franz X., Aberle, Judith H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989350/
https://ncbi.nlm.nih.gov/pubmed/29899743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01196
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