Wird geladen...

An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio

Despite availability of a diverse range of anti-epileptic drugs (AEDs), only about two-thirds of epilepsy patients respond well to drug treatment. Thus, novel targets are required to catalyse the design of next-generation AEDs. Manipulation of neuron firing-rate homoeostasis, through enhancing Pumil...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Neurogenet
Hauptverfasser: Lin, Wei-Hsiang, He, Miaomiao, Fan, Yuen Ngan, Baines, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989157/
https://ncbi.nlm.nih.gov/pubmed/29718742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01677063.2018.1465570
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!