Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells

Background: Viral oncogenes and mutated proto-oncogenes are potent drivers of cancer malignancy. Downstream of the oncogenic trigger are alterations in protein properties that give rise to cellular transformation and the acquisition of malignant cellular phenotypes. Developments in mass spectrometry...

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Udgivet i:Wellcome Open Res
Main Authors: Ly, Tony, Endo, Aki, Brenes, Alejandro, Gierlinski, Marek, Afzal, Vackar, Pawellek, Andrea, Lamond, Angus I.
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Limited 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989152/
https://ncbi.nlm.nih.gov/pubmed/29904729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14392.1
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