LOSS OF RUNX1 IS ASSOCIATED WITH AGGRESSIVE LUNG ADENOCARCINOMAS

The mammalian runt-related factor 1 (RUNX1) is a master transcription factor that regulates lineage specification of hematopoietic stem cells. RUNX1 translocations result in the development of myeloid leukemias. Recently, RUNX1 has been implicated as a tumor suppressor in other cancers. We postulate...

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Pubblicato in:J Cell Physiol
Autori principali: Ramsey, Jon, Butnor, Kelly, Peng, Zhihua, Leclair, Tim, van der Velden, Jos, Stein, Gary, Lian, Jane, Kinsey, C. Matthew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989135/
https://ncbi.nlm.nih.gov/pubmed/28926105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26201
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