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Multiple Frequency Saturation Pulses Reduce CEST Acquisition Time for Quantifying Conformational Exchange in Biomolecules

Exchange between conformational states is required for biomolecular catalysis, allostery, and folding. A variety of NMR experiments have been developed to quantify motional regimes ranging from nanoseconds to seconds. In this work, we describe an approach to speed up the acquisition of chemical exch...

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Bibliografiske detaljer
Udgivet i:J Biomol NMR
Main Authors: Leninger, Maureen, Marsiglia, William M., Jerschow, Alexej, Traaseth, Nathaniel J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989009/
https://ncbi.nlm.nih.gov/pubmed/29796789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-018-0186-1
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